Dipeptidyl-peptidase 3 protects oxygen-glucose deprivation/reoxygenation-injured hippocampal neurons by suppressing apoptosis, oxidative stress and inflammation via modulation of Keap1/Nrf2 signaling.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107595
Abstract: Dipeptidyl-peptidase 3 (DPP3) plays a key role in regulating apoptosis, oxidative stress and inflammation under various pathological conditions, however, whether DPP3 regulates apoptosis and oxidative stress in neurons undergoing cerebral ischemia/reperfusion injury has not yet… read more here.
Keywords: apoptosis oxidative; dpp3; stress inflammation; oxidative stress ... See more keywords
DPP3 expression promotes cell proliferation and migration in vitro and tumour growth in vivo, which is associated with poor prognosis of oesophageal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.3892/or.2022.8446
Abstract: Dipeptidyl peptidase III (DPP3), a zinc-dependent metallopeptidase, is upregulated in a variety of malignancies. However, little is known about its roles in the pathogenesis of these malignancies. The present study was designed to investigate the… read more here.
Keywords: proliferation migration; cell proliferation; tumour growth; dpp3 ... See more keywords