Differentiation of human dental pulp stem cells into neuronal by resveratrol
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10835
Abstract: Dental pulp stem cells (DPSCs) have been proposed as a promising source of stem cells in nerve regeneration due to their close embryonic origin and ease of harvest. Resveratrol (RSV) is a natural polyphenolic and… read more here.
Keywords: dpscs; differentiation; dental pulp; pulp stem ... See more keywords
Role of Ku70 in the apoptosis of inflamed dental pulp stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1167-2
Abstract: AimThe study aimed to investigate the effects of DNA repair proteins on cell apoptosis in human DPSCs during inflammation.MethodsLipopolysaccharide (LPS) was used to stimulate inflammation in dental pulp in vivo and in vitro. We identified… read more here.
Keywords: role ku70; dna repair; repair proteins; dpscs ... See more keywords
Betamethasone suppresses the inflammatory response in LPS-stimulated dental pulp cells through inhibition of NF-κB.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.11.022
Abstract: OBJECTIVE This study aimed to investigate the anti-inflammatory effect of betamethasone on LPS-stimulated human dental pulp stem cells (DPSCs) and its associated mechanism. The osteo-/odontogenic differentiation and osteoclast effect of betamethasone on DPSCs and stem… read more here.
Keywords: lps stimulated; effect betamethasone; betamethasone; dpscs ... See more keywords
Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c01379
Abstract: Acute spinal cord injury (SCI) induces severe neuroinflammation, which increases intermediary filaments and neurodegeneration. Previous studies have shown that a basic fibroblast growth factor (bFGF) and dental pulp stem cells (DPSCs) contribute to a protective… read more here.
Keywords: dpscs; bfgf dpscs; cord injury; spinal cord ... See more keywords
Metabolism as an early predictor of DPSCs aging
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-018-37489-4
Abstract: Tissue resident adult stem cells are known to participate in tissue regeneration and repair that follows cell turnover, or injury. It has been well established that aging impedes the regeneration capabilities at the cellular level,… read more here.
Keywords: analysis identified; dpscs; stem cell; stem ... See more keywords
IFN-γ regulates human dental pulp stem cells behavior via NF-κB and MAPK signaling
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40681
Abstract: During caries, dental pulp expresses a range of pro-inflammatory cytokines in response to the infectious challenge. Interferon gamma (IFN-γ) is a dimerized soluble cytokine, which is critical for immune responses. Previous study has demonstrated that… read more here.
Keywords: stem cells; pulp; dpscs; dental pulp ... See more keywords
The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200210
Abstract: Abstract Dental pulp stem cells (DPSCs) regenerate injured/diseased pulp tissue and deposit tertiary dentin. DPSCs stress response can be activated by exposing cells to the monomer triethyleneglycol dimethacrylate (TEGDMA) and inducing the DNA-damage inducible transcript… read more here.
Keywords: pulp stem; self renewal; pulp; dpscs ... See more keywords
The Role of Neuropilin-1-FYN Interaction in Odontoblast Differentiation of Dental Pulp Stem Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular reprogramming"
DOI: 10.1089/cell.2017.0041
Abstract: Abnormal odontoblast differentiation of dental pulp stem cells (DPSCs) caused by inflammation is closely related to the development of dental caries. Neuropilin-1 (NRP1) is one of the members of neuropilin family. It can combine with… read more here.
Keywords: dpscs; differentiation; odontoblast differentiation; dental pulp ... See more keywords
General Control Nonrepressed Protein 5 Modulates Odontogenic Differentiation Through NF-κB Pathway in Tumor Necrosis Factor-α-Mediated Impaired Human Dental Pulp Stem Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular reprogramming"
DOI: 10.1089/cell.2021.0113
Abstract: Dental pulp stem cells (DPSCs) from pulpitis patients showed defective osteogenic differentiation. However, as the most well-studied histone acetyltransferase, the impaired general control nonrepressed protein 5 (GCN5) plays essential roles in various developmental processes. The… read more here.
Keywords: dental pulp; dpscs; odontogenic differentiation; gcn5 ... See more keywords
Transplantation of Hepatocyte Growth Factor-Modified Dental Pulp Stem Cells Prevents Bone Loss in the Early Phase of Ovariectomy-Induced Osteoporosis.
Sign Up to like & getrecommendations! Published in 2018 at "Human gene therapy"
DOI: 10.1089/hum.2017.091
Abstract: Investigations based on mesenchymal stem cells (MSCs) for osteoporosis have attracted attention recently. MSCs can be derived from various tissues, such as bone marrow, adipose, umbilical cord, placenta, and dental pulp. Among these, dental pulp-derived… read more here.
Keywords: dpscs; bone loss; dental pulp; osteoporosis ... See more keywords
Overexpression of hepatocyte growth factor in dental pulp stem cells ameliorates the severity of psoriasis by reducing inflammatory responses.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells and development"
DOI: 10.1089/scd.2021.0129
Abstract: Psoriasis is an autoimmune disease still lacking standard treatment. And it has been demonstrated that mesenchymal stem cells (MSCs) are capable of immunoregulation. The underlying mechanism might involve the secretion of soluble cytokines, such as… read more here.
Keywords: dpscs; hgf; hepatocyte growth; psoriasis ... See more keywords