Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin
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DOI: 10.1038/s41467-021-23268-9
Abstract: Recent cryo-EM structures show the highly dynamic nature of the MLL1-NCP (nucleosome core particle) interaction. Functional implication and regulation of such dynamics remain unclear. Here we show that DPY30 and the intrinsically disordered regions (IDRs)… read more here.
Keywords: disordered regions; dpy30; mll set1; dpy30 ash2l ... See more keywords