Association between the HLA-DRB1*03:01-DQB1*02:01 haplotype and PF4/heparin antibodies.
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DOI: 10.1182/bloodadvances.2019000311
Abstract: HLA-DRB1*03:01-DQB1*02:01 haplotype patients develop higher anti–platelet factor 4/heparin (PF4/H) levels following IV heparin exposure. HLA-restricted antigen presentation may play a role in the formation of anti-PF4/H antibodies. read more here.
Keywords: drb1 dqb1; dqb1 haplotype; hla drb1;