KIR2DL5B and HLA DRB1*12 alleles seems to be associated with protection against HIV‐1 in serodiscordant couples in Burkina Faso
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27821
Abstract: The human immunodeficiency virus (HIV) belongs to the Retroviridae family and remains a public health problem in sub‐Saharan Africa. Recent reports from WHO have shown that 33 million people died from HIV infections. HIV is… read more here.
Keywords: protection hiv; drb1; hiv; hiv infection ... See more keywords
Frequency of human leukocyte antigens class II-DR alleles (HLA-DRB1) in Argentinian patients with early arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Rheumatology"
DOI: 10.1007/s10067-018-4319-4
Abstract: Patients with rheumatoid arthritis (RA) or undifferentiated arthritis (UA) in the CONAART database (Argentine Consortium for Early Arthritis) were assessed for genetic risk factors for RA, specifically for HLA-DRB1 alleles and the PTPN22 rs2476601 polymorphism… read more here.
Keywords: frequency; hla drb1; drb1; early arthritis ... See more keywords
The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.08.026
Abstract: Background Age-related brain changes are well-documented and influenced by genetics. Extensive research links apolipoprotein E (apoE) to brain function, with the E4 allele serving as a risk factor for brain disease, including Alzheimer's disease, and… read more here.
Keywords: network; age related; age; drb1 ... See more keywords
A specific immunity brain aging gene with a future
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DOI: 10.1016/j.ebiom.2018.08.044
Abstract: The paper by James et al. [1] here extends previous work from the DRB1*13 overrides the harmful effects of apoE4 on the brain, acquires Minnesota group [2] on the protective effect of certain Human Leukocyte… read more here.
Keywords: presence; drb1; specific immunity; gene ... See more keywords
Interaction of HLA-DRB1* alleles and CTLA4 (+49 AG) gene polymorphism in Autoimmune Thyroid Disease.
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DOI: 10.1016/j.gene.2017.11.057
Abstract: Autoimmune Thyroid Diseases (AITDs), including Hashimoto's thyroiditis (HT) and Graves' disease (GD), arise by the complex interaction of genes and environmental factors. The aim of present study was to study the susceptible associations of HLA-DRB1*… read more here.
Keywords: hla drb1; drb1; autoimmune thyroid; drb1 alleles ... See more keywords
Human Leukocyte Antigen class II polymorphisms among Croatian patients with type 1 diabetes and autoimmune polyglandular syndrome type 3 variant.
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DOI: 10.1016/j.gene.2018.06.083
Abstract: This study included 161 patients: 92 patients had type 1 diabetes (T1D) while 69 patients had a combination of T1D and autoimmune thyroiditis, the so-called autoimmune polyglandular syndrome type 3 variant (APS3v). Those patients, as… read more here.
Keywords: drb1 drb1; hla drb1; drb1; dqb1 ... See more keywords
P008 Uncommon or unexpected DRB1-DRB3/4/5 associations in NMDP-BE the match recruitment donor population
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DOI: 10.1016/j.humimm.2017.06.068
Abstract: Aim Since 2016, the National Marrow Donor Program (NMDP) has typed HLA-DRB3/4/5 on all newly recruited members added to the Be The Match Registry®. Gragert et al. published 6-locus haplotype frequencies in 2013 provided at… read more here.
Keywords: drb3; recruitment; drb1; p008 uncommon ... See more keywords
P125 HLA-A/C and HLA-B/DRB1 recombination in Chinese HAN population: Utility of next-generation sequencing method
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.185
Abstract: Aim To analyze the human leukocyte antigen complex class I (-A, -C, and -B) and class II (-DRB1, and -DQB1) linked haplotypes of Chinese Han population, and to study the recombination events of the five… read more here.
Keywords: chinese han; drb1; hla; han population ... See more keywords
P028 Importance of evaluating allele-level HLA typing of the donor to assess the immunological logistics of importing a renal allograft for highly sensitized recipient and facilitating a successful transplant
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DOI: 10.1016/j.humimm.2018.07.086
Abstract: Renal transplant candidates with more than 99% CPRA are at greater disadvantage for a match run. Even with a match-run, some of the allelic DSAs not used for Unacceptable Antigens [UA] entry criteria, could make… read more here.
Keywords: transplant; recipient; drb1; hla ... See more keywords
P162 Progress towards gene editing of HLA-DRB1∗04:01 by CRISPR/Cas9
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DOI: 10.1016/j.humimm.2018.07.219
Abstract: Aim The HLA-DRB1 locus represents the greatest genetic risk factor for susceptibility for rheumatoid arthritis (RA). We have refined this genetic association to a single amino acid polymorphism at position 71 that is associated with… read more here.
Keywords: crispr cas9; gene; hla drb1; drb1 ... See more keywords
HLA study in Amerindian Bolivia La Paz Aymaras.
Sign Up to like & getrecommendations! Published in 2020 at "Human immunology"
DOI: 10.1016/j.humimm.2020.04.005
Abstract: Aymara people has been a relatively homogeneous group since Spanish Conquest by 1,532 CE, even if previously represented a group of various cultural defined populations who gave rise to them. They were and are established… read more here.
Keywords: titikaka lake; drb1; dqb1; bolivia ... See more keywords