Haplotype‐dependent HLA‐DRB1‐DQB1 susceptibility to occult HBV infection in Xi'an Han population
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2102
Abstract: Occult hepatitis B virus (HBV) infection (OBI) is primarily characterized by the persistence of HBV‐DNA in the liver tissues and/or in the serum without detectable HBsAg. Human leukocyte antigen (HLA) polymorphisms have been found to… read more here.
Keywords: hbv infection; drb1 dqb1; hla drb1; hla ... See more keywords
Contribution of HLA class II genes, DRB4*01:01, DRB1*07:01, and DQB1*03:03:2 to clinical features of Vitiligo disease in Iranian population.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06855-3
Abstract: BACKGROUND Vitiligo is a multifactorial depigmentation condition, which is due to skin melanocyte destruction. Increased expression of HLA class II genes in patients with pre-lesions of Vitiligo suggests a crucial role for the participation of… read more here.
Keywords: vitiligo; drb4 drb1; drb1 dqb1; hla class ... See more keywords
P118 Presence of HLA extended haplotypes and KIR association in health and diseases in South India
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.178
Abstract: Aim To study the HLA/KIR interactions in health (HC) and disease (DC) (T1DM, T2DM, AITD, CAD, IS, PKF and AKF) cohorts with reference to two extended haplotypes (EHs). Methods Individuals with ‘DRB1∗07-DQB1∗02’ (HC = 168/1353; DC = 271/1376) and… read more here.
Keywords: kir; drb1 dqb1; south india; extended haplotypes ... See more keywords
Study of HLA genes in Mexico Mayo/Yoremes Amerindians: Further support of gene exchange with Pacific Islanders.
Sign Up to like & getrecommendations! Published in 2020 at "Human immunology"
DOI: 10.1016/j.humimm.2020.02.012
Abstract: Mexican Mayo Amerindians live in southern Sonora and North Sinaloa states. They probably come from North or are related to First American Inhabitants established further North. A non-related sample of them have volunteered to HLA… read more here.
Keywords: drb1 dqb1; pacific islanders; hla drb1; hla ... See more keywords
The influence of population stratification on genetic markers associated with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43513
Abstract: Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting… read more here.
Keywords: t1d; drb1 dqb1; type diabetes; population stratification ... See more keywords
Influence of HLA Class II Alleles and DRB1-DQB1 Haplotypes on Rheumatoid Arthritis Susceptibility and Autoantibody Status in the Chinese Han Population.
Sign Up to like & getrecommendations! Published in 2021 at "Immunological investigations"
DOI: 10.1080/08820139.2021.1918708
Abstract: Human leukocyte antigen (HLA) class II alleles are considered to play a key role in the progress of rheumatoid arthritis (RA). This study was carried out to investigate the presence of HLA class II alleles… read more here.
Keywords: dqb1; hla drb1; drb1 dqb1; hla class ... See more keywords
Association Between HLA Polymorphisms and Sympathetic Ophthalmia in Han Chinese.
Sign Up to like & getrecommendations! Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2205930
Abstract: PURPOSE Sympathetic ophthalmia (SO) is considered as an autoimmune disease with unclear mechanisms. This study investigated the relationship between HLA polymorphisms and SO. METHODS HLA typing was performed using the LABType reverse SSO DNA typing… read more here.
Keywords: drb1 dqb1; hla; sympathetic ophthalmia; association hla ... See more keywords
Six novel HLA‐B, ‐DRB1, and ‐DQB1 alleles identified in Brazilian individuals
Sign Up to like & getrecommendations! Published in 2018 at "HLA"
DOI: 10.1111/tan.13329
Abstract: The novel HLA alleles B*40:331, B*40:343, B*42:24, DRB1*01:74, DQB1*03:243, and DQB1*03:02:20 were identified in Brazilian individuals. read more here.
Keywords: brazilian individuals; drb1 dqb1; identified brazilian; novel hla ... See more keywords
HLA‐A, ‐B, ‐C, ‐DRB1, and ‐DQB1 allele and haplotype frequencies: An analysis of umbilical cord blood units at the Barcelona Cord Blood Bank
Sign Up to like & getrecommendations! Published in 2019 at "HLA"
DOI: 10.1111/tan.13644
Abstract: Allele‐level HLA compatibility in cord blood transplantation has been associated with better transplant outcomes and is recommended as a selection criterion. It is also a crucial aspect for other therapeutic applications involving cord blood‐derived cells.… read more here.
Keywords: drb1 dqb1; cord blood; cord; hla ... See more keywords
Using next‐generation sequencing for characterising HLA‐DRB1 and DQB1 loci in a cohort of Colombian women
Sign Up to like & getrecommendations! Published in 2019 at "HLA"
DOI: 10.1111/tan.13672
Abstract: The Colombian population is characterised by a high genetic diversity, secondary to the ethnic mixture arising from colonisation. Unfortunately, few reports are available regarding HLA‐DRB1 and DQB1 diversity in Colombia to date. HLA‐DRB1 and DQB1… read more here.
Keywords: drb1 dqb1; hla drb1; dqb1; population ... See more keywords
Association between the HLA-DRB1*03:01-DQB1*02:01 haplotype and PF4/heparin antibodies.
Sign Up to like & getrecommendations! Published in 2019 at "Blood advances"
DOI: 10.1182/bloodadvances.2019000311
Abstract: HLA-DRB1*03:01-DQB1*02:01 haplotype patients develop higher anti–platelet factor 4/heparin (PF4/H) levels following IV heparin exposure. HLA-restricted antigen presentation may play a role in the formation of anti-PF4/H antibodies. read more here.
Keywords: drb1 dqb1; dqb1 haplotype; hla drb1;