Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b01002
Abstract: The preparation of PLGA rods for sustained release applications via a hot-melt extrusion process employs heat and mechanical shear. Understanding protein stability and degradation mechanisms at high temperature in the solid state is therefore important… read more here.
Keywords: solid state; aggregation; dried formulations; spray dried ... See more keywords
Safety of frozen and freeze‐dried formulations of the lesser mealworm (Alphitobius diaperinus larva) as a Novel food pursuant to Regulation (EU) 2015/2283
Sign Up to like & getrecommendations! Published in 2022 at "EFSA Journal"
DOI: 10.2903/j.efsa.2022.7325
Abstract: Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen and dried formulations from whole lesser mealworm (Alphitobius… read more here.
Keywords: lesser mealworm; food; panel; alphitobius diaperinus ... See more keywords
Spray Dried Formulations for Inhalation—Meaningful Characterisation of Powder Properties
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12010014
Abstract: Spray drying as a particle engineering technique is of increasing interest in the field of inhalation and is already being utilised e.g., for the PulmoSphereTM products. As spray dried particles tend to agglomerate and are… read more here.
Keywords: inhalation meaningful; dried formulations; powder; spray dried ... See more keywords