Articles with "drift tube" as a keyword



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Utilizing Drift Tube Ion Mobility Spectrometry for the Evaluation of Metabolites and Xenobiotics.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0030-6_2

Abstract: Metabolites and xenobiotics are small molecules with a molecular weight that often falls below 600 Da. Over the last few decades, multiple small molecule databases have been curated listing structures, masses, and fragmentation spectra possible in… read more here.

Keywords: spectrometry; drift tube; small molecules; metabolites xenobiotics ... See more keywords
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Untargeted Differential Metabolomics Analysis Using Drift Tube Ion Mobility-Mass Spectrometry.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0030-6_3

Abstract: Mass spectrometry-based metabolomics is being increasingly applied to a number of applications, including the fields of clinical, industrial, plant, and nutritional science. Several improvements have advanced the field considerably over the past decade, including ultra-high… read more here.

Keywords: mass spectrometry; drift tube; mass; mobility mass ... See more keywords
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Enhancing Separation and Constriction of Ion Mobility Distributions in Drift Tubes at Atmospheric Pressure Using Varying Fields.

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Published in 2022 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.2c00467

Abstract: A linearly decreasing electric field has been previously proven to be effective for diffusional correction of ions in a varying field drift tube (VFDT) system, leading to higher resolving powers compared to a conventional drift… read more here.

Keywords: atmospheric pressure; power; resolving power; drift tube ... See more keywords
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Separation and Collision Cross Section Measurements of Protein Complexes Afforded by a Modular Drift Tube Coupled to an Orbitrap Mass Spectrometer.

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Published in 2022 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.2c01653

Abstract: New developments in analytical technologies and biophysical methods have advanced the characterization of increasingly complex biomolecular assemblies using native mass spectrometry (MS). Ion mobility methods, in particular, have enabled a new dimension of structural information… read more here.

Keywords: drift tube; separation; collision cross; mass ... See more keywords
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An Interlaboratory Evaluation of Drift Tube Ion Mobility-Mass Spectrometry Collision Cross Section Measurements.

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Published in 2017 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.7b01729

Abstract: Collision cross section (CCS) measurements resulting from ion mobility-mass spectrometry (IM-MS) experiments provide a promising orthogonal dimension of structural information in MS-based analytical separations. As with any molecular identifier, interlaboratory standardization must precede broad range… read more here.

Keywords: drift tube; ion mobility; ion; mobility mass ... See more keywords
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Improving Ion Mobility Mass Spectrometry of Proteins through Tristate Gating and Optimization of Multiplexing Parameters.

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Published in 2022 at "Journal of the American Society for Mass Spectrometry"

DOI: 10.1021/jasms.2c00274

Abstract: Coupling drift tube ion mobility (IM) to Fourier transform mass spectrometry (FT-MS) affords the opportunity for gas-phase separation of ions based on size and conformation with high-resolution mass analysis. However, combining IM and FT-MS is… read more here.

Keywords: drift tube; mass spectrometry; ion mobility; mass ... See more keywords
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Focused ion beam fabrication of Janus bimetallic cylinders acting as drift tube Zernike phase plates for electron microscopy

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Published in 2021 at "Journal of Applied Physics"

DOI: 10.1063/5.0050055

Abstract: Modern nanotechnology techniques offer new opportunities for fabricating structures and devices at the micron and sub-micron level. Here, we use focused ion beam techniques to realize drift tube Zernike phase plates for electrons, whose operation… read more here.

Keywords: tube zernike; microscopy; ion beam; zernike phase ... See more keywords
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Cosmic-Ray Muon Tomography Setup: Long-Term Life of Drift Tube Chambers

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Published in 2020 at "Physics of Atomic Nuclei"

DOI: 10.1134/s1063778820020088

Abstract: Abstract For investigation of the cosmic muon scattering tomography (MST) concept at NRC ‘‘Kurchatov Institute’’—IHEP the large-scale setup has been constructed. The setup includes 8 planes ( $$3\times 3$$ m $${}^{2}$$ each) of 3-layer drift… read more here.

Keywords: tube chambers; setup long; drift; long term ... See more keywords
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Contribution of Capillary Zone Electrophoresis Hyphenated with Drift Tube Ion Mobility Mass Spectrometry as a Complementary Tool to Microfluidic Reversed Phase Liquid Chromatography for Antigen Discovery

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232113350

Abstract: The discovery of new antigens specific to multiple myeloma that could be targeted by novel immunotherapeutic approaches is currently of great interest. To this end, it is important to increase the number of proteins identified… read more here.

Keywords: drift tube; zone electrophoresis; capillary zone; antigen discovery ... See more keywords