Genomic and epigenetic landscapes drive CRISPR-based genome editing in Bifidobacterium
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DOI: 10.1073/pnas.2205068119
Abstract: Significance Genome engineering in Bifidobacterium remains challenging, despite successful CRISPR deployment in other bacteria, hindering the comprehensive understanding of the molecular mechanisms of health-promoting effects. In this study, we adapted existing CRISPR effectors and editing… read more here.
Keywords: genome editing; drive crispr; bifidobacterium; genomic epigenetic ... See more keywords