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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-50354-5
Abstract: Maintenance of NAD pools is critical for neuronal survival. The capacity to maintain NAD pools declines in neurodegenerative disease. We identify that low NMNAT2, the critical neuronal NAD producing enzyme, drives retinal susceptibility to neurodegenerative…
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Keywords:
drive neuronal;
neuronal nad;
nad production;
nmnat2 druggable ... See more keywords