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   Articles with "driven biocatalytic" as a keyword



Construction of dual cofactor‐driven biocatalytic system for effective production of chiral amino acids

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recommendations! Published in 2025 at "AIChE Journal"

DOI: 10.1002/aic.18894

Abstract: Asymmetric reductive amination is essential for producing chiral amino acids, yet optimizing intracellular cofactor utilization for this process remains challenging. Herein, we developed a dual cofactor‐driven biocatalytic system (DuCoCat) that utilizes both intracellular NAD(H) and… read more here.

Keywords: system; cofactor; dual cofactor; driven biocatalytic ... See more keywords

A hydrogen-driven biocatalytic approach to recycling synthetic analogues of NAD(P)H.

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recommendations! Published in 2022 at "Chemical communications"

DOI: 10.1039/d2cc02411j

Abstract: We demonstrate a recycling system for synthetic nicotinamide cofactor analogues using a soluble hydrogenase with turnover number of >1000 for reduction of the cofactor analogues by H2. Coupling this system to an ene reductase, we… read more here.

Keywords: driven biocatalytic; hydrogen driven; synthetic analogues; biocatalytic approach ... See more keywords

Light-driven biocatalytic oxidation

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recommendations! Published in 2022 at "Chemical Science"

DOI: 10.1039/d2sc03483b

Abstract: Enzymes are the catalyst of choice for highly selective reactions, offering nature-inspired approaches for sustainable chemical synthesis. Oxidative enzymes (e.g., monooxygenases, peroxygenases, oxidases, or dehydrogenases) catalyze a variety of enantioselective oxyfunctionalization and dehydrogenation reactions under… read more here.

Keywords: oxidation; biocatalytic oxidation; driven biocatalytic; light driven ... See more keywords

A deamination-driven biocatalytic cascade for the synthesis of ribose-1-phosphate

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recommendations! Published in 2024 at "Green Chemistry"

DOI: 10.1039/d4gc02955k

Abstract: Ribose-1-phosphate (Rib1P) is a key substrate for the synthesis of difficult-to-access nucleoside analogues by nucleoside phosphorylases. However, its use in preparative synthesis is hampered by low yields and low selectivity... read more here.

Keywords: biocatalytic cascade; ribose phosphate; deamination driven; synthesis ... See more keywords