An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1921786117
Abstract: Significance MYC is a transcriptional regulator that controls much of the coding and noncoding transcriptome. It is also an oncoprotein that functions as a driver in numerous human cancers. The mechanism of this oncogenic activity… read more here.
Keywords: repressor; cell proliferation; proliferation; myc driven ... See more keywords
Cell ontology in an age of data-driven cell classification
Sign Up to like & getrecommendations! Published in 2017 at "BMC Bioinformatics"
DOI: 10.1186/s12859-017-1980-6
Abstract: BackgroundData-driven cell classification is becoming common and is now being implemented on a massive scale by projects such as the Human Cell Atlas. The scale of these efforts poses a challenge. How can the results… read more here.
Keywords: driven cell; cell classification; ontology; data driven ... See more keywords