Phosphofructokinases Axis Controls Glucose-Dependent mTORC1 Activation Driven by E2F1
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DOI: 10.1016/j.isci.2019.09.040
Abstract: Summary Cancer cells rely on mTORC1 activity to coordinate mitogenic signaling with nutrients availability for growth. Based on the metabolic function of E2F1, we hypothesize that glucose catabolism driven by E2F1 could participate on mTORC1… read more here.
Keywords: mtorc1 activity; mtorc1 activation; activation; driven e2f1 ... See more keywords