Identification of methylation‐driven genes related to prognosis in clear‐cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29046
Abstract: With the participation of the existing treatment methods, the prognosis of advanced clear‐cell renal cell carcinoma (ccRCC) is poor. More evidence indicates the presence of methylation in ccRCC cancer cells, but there is a lack… read more here.
Keywords: methylation; ccrcc; prognosis; methylation driven ... See more keywords
Identification of DNA methylation-driven genes and construction of a nomogram to predict overall survival in pancreatic cancer
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DOI: 10.1186/s12864-021-08097-w
Abstract: Background The incidence and mortality of pancreatic cancer (PC) has gradually increased. The aim of this study was to identify survival-related DNA methylation (DNAm)-driven genes and establish a nomogram to predict outcomes in patients with… read more here.
Keywords: risk score; dna methylation; survival; driven genes ... See more keywords
Identification of methylation-driven genes prognosis signature and immune microenvironment in uterus corpus endometrial cancer
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DOI: 10.1186/s12935-021-02038-z
Abstract: Background Uterus corpus endometrial cancer (UCEC) is the main malignant tumor in gynecology, with a high degree of heterogeneity, especially in terms of prognosis and immunotherapy efficacy. DNA methylation is one of the most important… read more here.
Keywords: methylation; prognosis; analysis; methylation driven ... See more keywords
Molecular Characterization, Tumor Microenvironment Association, and Drug Susceptibility of DNA Methylation-Driven Genes in Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.837919
Abstract: Accumulating evidence suggests that DNA methylation has essential roles in the development of renal cell carcinoma (RCC). Aberrant DNA methylation acts as a vital role in RCC progression through regulating the gene expression, yet little… read more here.
Keywords: methylation; methylation driven; dna methylation; rcc ... See more keywords
A Robust Prognostic Gene Signature Based on eRNAs-Driven Genes in Prostate Cancer
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DOI: 10.3389/fgene.2021.676845
Abstract: Prostate cancer (PCa) is the second most common malignancy in men, but its exact pathogenetic mechanisms remain unclear. This study explores the effect of enhancer RNAs (eRNAs) in PCa. Firstly, we screened eRNAs and eRNA… read more here.
Keywords: erna driven; driven genes; cancer; gene signature ... See more keywords
Identification and analysis of DNA methylation-driven signatures for prognostic and immune microenvironments evaluation in hepatocellular carcinoma
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DOI: 10.3389/fgene.2022.1022078
Abstract: Liver cancer is the main reason of cancer deaths globally, with an unfavorable prognosis. DNA methylation is one of the epigenetic modifications and maintains the right adjustment of gene expression and steady gene silencing. We… read more here.
Keywords: methylation; methylation driven; dna methylation; analysis ... See more keywords
A novel prognostic model based on six methylation-driven genes predicts overall survival for patients with clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.996291
Abstract: Clear cell renal cell carcinoma (ccRCC) is a lethal urological malignancy. DNA methylation is involved in the regulation of ccRCC occurrence and progression. This study aimed to establish a prognostic model based on DNA methylation… read more here.
Keywords: methylation; methylation driven; cell; overall survival ... See more keywords
Integrative Analysis of Identifying Methylation-Driven Genes Signature Predicts Prognosis in Colorectal Carcinoma
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DOI: 10.3389/fonc.2021.629860
Abstract: Background Aberrant DNA methylation is a critical regulator of gene expression and plays a crucial role in the occurrence, progression, and prognosis of colorectal cancer (CRC). We aimed to identify methylation-driven genes by integrative epigenetic… read more here.
Keywords: methylation; driven genes; prognosis; analysis ... See more keywords
Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas.
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DOI: 10.3892/mmr.2019.10771
Abstract: RNA‑Sequencing and methylation data for hepatocellular carcinoma (HCC) were downloaded from The Cancer Genome Atlas (TCGA). The aberrantly expressed methylation‑driven genes in HCC and normal tissues were identified using the Limma package and the MethylMix… read more here.
Keywords: methylation; risk; model; methylation driven ... See more keywords