Hypoxia driven glycation: Mechanisms and therapeutic opportunities.
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DOI: 10.1016/j.semcancer.2017.05.008
Abstract: Tumor masses are deprived of oxygen and characterized by enhanced glucose uptake followed by glycolysis. Elevated glucose levels induce non-enzymatic glycosylation or glycation of proteins which leads to accumulation of advanced glycation end products (AGE).… read more here.
Keywords: hypoxia driven; age; driven glycation; cancer ... See more keywords