Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "Nature Medicine"
DOI: 10.1038/nm.4463
Abstract: Multiple immune-cell types can infiltrate tumors and promote progression and metastasis through different mechanisms, including immunosuppression. How distinct genetic alterations in tumors affect the composition of the immune landscape is currently unclear. Here, we characterized… read more here.
Keywords: immune landscapes; driven immune; diverse genetic; progression ... See more keywords
Abstract 2494: Heterogeneous tumor-driven immune landscapes between lung adenocarcinomas in ever and never-smokers
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2494
Abstract: To depict the genomic and immune landscapes of lung adenocarcinomas (ADCs) in ever and never-smokers and guide the design of immunotherapy strategies, we applied multiple deconvolution methods that allow the identification of immune cell infiltration… read more here.
Keywords: never smokers; tumor driven; ever smokers; lung ... See more keywords
Efficacy of minimal residual disease driven immune-intervention after allogeneic hematopoietic stem cell transplantation for high-risk chronic lymphocytic leukemia: results of a prospective multicenter trial
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DOI: 10.3324/haematol.2019.239566
Abstract: Allogeneic hematopoietic stem cell transplantation (HSCT) remains a potentially curative and useful strategy in high-risk relapsing chronic lymphocytic leukemia (CLL). Minimal residual disease (MRD) assessment at 12 months (M12) post-HSCT is predictive of relapse. This… read more here.
Keywords: risk; high risk; disease; driven immune ... See more keywords