Non-canonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y11 receptor.
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DOI: 10.1093/jleuko/qiaf010
Abstract: Extracellular ATP released from dying cells, including tumor cells, is a key mediator of inflammation and tolerance by binding to purinergic receptors on dendritic cells, resulting in inflammasome activation (via P2X7R), dendritic cell maturation (via… read more here.
Keywords: upregulation; dioxygenase; driven indoleamine; atp driven ... See more keywords