Targeting protein folding in N‐Myc‐driven medulloblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13395
Abstract: Selective targeting of N‐Myc‐driven Sonic hedgehog (SHH) medulloblastoma has been a challenge for many years and, despite decades of research, few targeted therapy opportunities exist. Recently, Kuzuoglu‐Ozturk et al. characterized the translatome of N‐Myc‐driven medulloblastoma… read more here.
Keywords: protein folding; targeting protein; folding myc; myc driven ... See more keywords
Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells
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DOI: 10.1038/onc.2017.110
Abstract: Group3 medulloblastoma (MBG3) that predominantly occur in young children are usually associated with MYC amplification and/or overexpression, frequent metastasis and a dismal prognosis. Physiologically relevant MBG3 models are currently lacking, making inferences related to their… read more here.
Keywords: embryonic cerebellar; novel myc; myc driven; driven medulloblastoma ... See more keywords