Nanomedicine-driven molecular targeting, drug delivery, and therapeutic approaches to cancer chemoresistance.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.12.016
Abstract: Cancer cell resistance to chemotherapeutics (chemoresistance) poses a significant clinical challenge that oncology research seeks to understand and overcome. Multiple anticancer drugs and targeting agents can be incorporated in nanomedicines, in addition to different treatment… read more here.
Keywords: chemoresistance; driven molecular; molecular targeting; drug ... See more keywords
Light-Driven Molecular Whirligig.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c02547
Abstract: A unidirectional light-driven rotary motor was looped in a figure-of-eight molecule by linking two polymer chains between its stator and rotor parts. By properly tuning the size of these linkers, clockwise rotation of the motor… read more here.
Keywords: molecular whirligig; polymer chains; motor; driven molecular ... See more keywords
Transamidation-Driven Molecular Pumps
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06807
Abstract: We report a new class of synthetic molecular pumps that use a stepwise information ratchet mechanism to achieve the kinetic gating required to sequester their macrocyclic substrates from bulk solution. Threading occurs as a result… read more here.
Keywords: transamidation; rotaxane; transamidation driven; pump ... See more keywords
A Nitrogen Out-of-Plane (NOOP) Mechanism for Imine-Based Light-Driven Molecular Motors.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c00275
Abstract: Light-driven molecular motors have generated considerable interest due to their potential applications in material and biological systems. Recently, Greb and Lehn reported a new class of molecular motors, chiral N-alkyl imines, which undergo unidirectional rotation… read more here.
Keywords: molecular motors; plane; imine; mechanism ... See more keywords
Light-driven molecular trap enables bidirectional manipulation of dynamic covalent systems
Sign Up to like & getrecommendations! Published in 2018 at "Nature Chemistry"
DOI: 10.1038/s41557-018-0106-8
Abstract: Bond formation between two molecular entities in a closed system strictly obeys the principle of microscopic reversibility and occurs in favour of the thermodynamically more stable product. Here, we demonstrate how light can bypass this… read more here.
Keywords: molecular trap; driven molecular; dynamic covalent; covalent systems ... See more keywords
Humidity driven molecular switch based on photoluminescent DyIIICoIII single-molecule magnets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry C"
DOI: 10.1039/c8tc06630b
Abstract: Functional materials incorporating cyanido-bridged DyIIICoIII molecules combine visible photoluminescence and slow magnetic relaxation, both switchable by the level of humidity within the reversible room temperature dehydration process. read more here.
Keywords: based photoluminescent; driven molecular; humidity driven; photoluminescent dyiiicoiii ... See more keywords
Design and photoisomerization dynamics of a new family of synthetic 2-stroke light driven molecular rotary motors.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc01955c
Abstract: A new family of light driven molecular rotary motors, which can be synthesized from easily available precursor compounds and which are capable of completing a full 360° revolution by two photoisomerization steps only, is proposed.… read more here.
Keywords: rotary motors; driven molecular; new family; light driven ... See more keywords
Light driven molecular lock comprises a Ru(bpy)2(hpip) complex and cucurbit[8]uril
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d0ra10940a
Abstract: Upon light irradiation, complex 1 was transformed from a U-shaped conformation to an interlocked complex. read more here.
Keywords: driven molecular; bpy hpip; comprises bpy; light driven ... See more keywords
Antiresonant quantum transport in ac-driven molecular nanojunctions
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review B"
DOI: 10.1103/physrevb.97.214303
Abstract: We calculate the electric charge current flowing through a vibrating molecular nanojunction, which is driven by an ac voltage, in its regime of nonlinear oscillations. Without loss of generality, we model the junction by a… read more here.
Keywords: driven molecular; quantum transport; molecular nanojunctions; antiresonant quantum ... See more keywords
Design and Nonadiabatic Photoisomerization Dynamics Study of a Three-Stroke Light-Driven Molecular Rotary Motor
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073908
Abstract: Working cycle of conventional light-driven molecular rotary motors (LDMRMs), especially Feringa-type motors, usually have four steps, two photoisomerization steps, and two thermal helix inversion (THI) steps. THI steps hinder the ability of the motor to… read more here.
Keywords: photoisomerization; nonadiabatic photoisomerization; three stroke; molecular rotary ... See more keywords