Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis
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DOI: 10.1080/15548627.2018.1450708
Abstract: ABSTRACT Defects in basal autophagy limit the nutrient supply from recycling of intracellular constituents. Despite our understanding of the prosurvival role of macroautophagy/autophagy, how nutrient deprivation, caused by compromised autophagy, affects oncogenic KRAS-driven tumor progression… read more here.
Keywords: tumorigenesis; oncogenic kras; driven tumor; autophagic reliance ... See more keywords