Articles with "driver tumorigenesis" as a keyword



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MENIN loss as a tissue-specific driver of tumorigenesis

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Published in 2018 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2017.09.032

Abstract: The MEN1 gene encodes MENIN, a tumor suppressor that plays a role in multiple cellular processes. Germline and somatic mutations in MEN1 have been identified in hereditary and sporadic tumors of neuroendocrine origins suggesting context-specific… read more here.

Keywords: tissue specific; menin loss; specific driver; driver tumorigenesis ... See more keywords