Allostery: Allosteric Cancer Drivers and Innovative Allosteric Drugs.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2022.167569
Abstract: Here, we discuss the principles of allosteric activating mutations, propagation downstream of the signals that they prompt, and allosteric drugs, with examples from the Ras signaling network. We focus on Abl kinase where mutations shift… read more here.
Keywords: allosteric cancer; innovative allosteric; allosteric drugs; drivers innovative ... See more keywords