DNA replication initiation drives focal mutagenesis and rearrangements in human cancers
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DOI: 10.1038/s41467-024-55148-3
Abstract: The rate and pattern of mutagenesis in cancer genomes is significantly influenced by DNA accessibility and active biological processes. Here we show that efficient sites of replication initiation drive and modulate specific mutational processes in… read more here.
Keywords: replication; initiation; drives focal; replication initiation ... See more keywords