Molecular Mechanisms of IRE1α-ASK1 Pathway Reactions to Unfolded Protein Response in DRN Neurons of Post-Traumatic Stress Disorder Rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0895-z
Abstract: The goal of this study was to further elucidate the molecular mechanisms of post-traumatic stress disorder (PTSD) pathogenesis and to provide experimental evidence for new drug targets for effective PTSD treatment. Expression changes of IRE1α,… read more here.
Keywords: control; drn neurons; stress; expression ... See more keywords
The Raphe Dopamine System: Roles in Salience Encoding, Memory Expression, and Addiction
Sign Up to like & getrecommendations! Published in 2021 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2021.01.002
Abstract: Dopamine (DA) neurons of the dorsal raphe nucleus (DRN) were traditionally viewed as an extension of the ventral tegmental area (VTA) DA population. While the VTA DA population is known to play important roles in… read more here.
Keywords: memory expression; dopamine; addiction; drn neurons ... See more keywords
Serotonin hyperpolarizes the dorsal raphe nucleus neurons of mice by activating G protein–coupled inward rectifier potassium channels
Sign Up to like & getrecommendations! Published in 2020 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001501
Abstract: Serotonin (5-HT) has an important role in the pathophysiology of the mood disorders like major depression and anxiety disorders in central nervous system. On the one hand, dorsal raphe nucleus (DRN) neurons send serotonergic projections… read more here.
Keywords: potassium; neurons mice; drn neurons; dorsal raphe ... See more keywords