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Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700374
Abstract: To explore and utilize the advantages of droplet‐based microfluidics, hydrodynamics, and mixing process within droplets traveling though the T junction channel and convergent–divergent sinusoidal microchannels are studied by numerical simulations and experiments, respectively. In the… read more here.
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Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201900047
Abstract: Microfluidics has made a very impressive progress in the past decades due to its unique and instinctive advantages. Droplet‐based microfluidic systems show excellent compatibility with many chemical and biological reagents and are capable of performing… read more here.
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1414-3_14
Abstract: Yarrowia lipolytica has emerged as an attractive solution for screening enzyme activities thanks to the numerous tools available for heterologous protein production and its strong secretory ability. Nowadays, activity screening for improved enzymes mostly relies… read more here.
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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6734-6_12
Abstract: We demonstrate an accurate and sensitive quantification of mutated KRAS oncogene in genomic DNA, using droplet-based microfluidics and digital PCR. read more here.
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Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1280-7
Abstract: We report the development and characterization of digital microfluidic (DMF) immobilized enzyme reactors (IMERs) for studying cytochrome P450 (CYP)-mediated drug metabolism on droplet scale. The on-chip IMERs consist of porous polymer (thiol-ene) monolith plugs prepared… read more here.
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Published in 2017 at "Biomedical Microdevices"
DOI: 10.1007/s10544-017-0165-4
Abstract: Direct antibiotic susceptibility tests (AST) are essential for rapid detection of bacterial infection and administration of appropriate antibiotics. Conventional AST systems are usually slow as they rely on cell growth for an indirect assessment of… read more here.
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Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.08.096
Abstract: ABSTRACT Droplet-based microfluidics enables the generation of uniform microdroplets at picoliter or nanoliter scale with high frequency (∼kHz) under precise control. The droplets can function as bioreactors for versatile chemical/biological study and analysis. Taking advantage… read more here.
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Published in 2019 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2018.09.043
Abstract: Abstract Droplet-based microfluidic extraction is a promising way for effective lanthanides extraction due to its outstanding mass transfer performance. The separation process can be greatly enhanced with the droplet-based microfluidic extraction technique. However, the interactions… read more here.
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Published in 2018 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2018.06.066
Abstract: S.K. acknowledges funding from the European Research Council under the ERC Starting Grant Agreement no. 677169–MicroParticleControl. F.C acknowledges FCT (postdoctoral fellowship [SFRH/BPD/96132/2013]) under the project POCI-01-0145-FEDER-006939 (Laboratory for Process Engineering, Environment, Biotechnology and Energy –… read more here.
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Published in 2019 at "Chemical Engineering Research and Design"
DOI: 10.1016/j.cherd.2019.02.007
Abstract: Abstract The present work was focused on the dynamic characterization of nanoparticles production under continuous flow in a droplet-based spiral-shaped microreactor. A novel drainage design was incorporated into the microreactor channel network for eliminating the… read more here.
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Published in 2017 at "International Journal of Multiphase Flow"
DOI: 10.1016/j.ijmultiphaseflow.2017.08.010
Abstract: Abstract Mixing is an essential operation in many microfluidic devices. Droplet-based micromixers utilize droplets for mixing enhancement. In the present study, a novel three-dimensional simulation is conducted which has the ability to capture not only… read more here.