Droplet Microfluidics for Microbial Biotechnology.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2020_140
Abstract: Droplet microfluidics has recently evolved as a prominent platform for high-throughput experimentation for various research fields including microbiology. Key features of droplet microfluidics, like compartmentalization, miniaturization, and parallelization, have enabled many possibilities for microbiology including… read more here.
Keywords: microbial biotechnology; biotechnology; microfluidics microbial; microbiology ... See more keywords
Ultrahigh-Throughput Screening of Metagenomic Libraries Using Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1826-4_2
Abstract: Droplet microfluidics enables the ultrahigh-throughput screening of the natural or man-made genetic diversity for industrial enzymes, with reduced reagent consumption and lower costs than conventional robotic alternatives. Here we describe an example of metagenomic screening… read more here.
Keywords: ultrahigh throughput; screening metagenomic; droplet microfluidics; throughput screening ... See more keywords
Droplet Microfluidics for High-Throughput Analysis of Antibiotic Susceptibility in Bacterial Cells and Populations
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of Chemical Research"
DOI: 10.1021/acs.accounts.1c00729
Abstract: Conspectus Antibiotic-resistant bacteria are an increasing concern both in everyday life and specialized environments such as healthcare. As the rate of antibiotic-resistant infections rises, so do complications to health and the risk of disability and… read more here.
Keywords: high throughput; resistance; droplet microfluidics; antibiotic susceptibility ... See more keywords
Particle Manipulation Methods in Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b01333
Abstract: This Feature describes the different particle manipulation techniques available in the droplet microfluidics toolbox to handle particles encapsulated inside droplets and to manipulate whole droplets. We address the advantages and disadvantages of the different techniques… read more here.
Keywords: particle manipulation; manipulation methods; droplet microfluidics; methods droplet ... See more keywords
Emerging Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.6b00848
Abstract: Droplet microfluidics generates and manipulates discrete droplets through immiscible multiphase flows inside microchannels. Due to its remarkable advantages, droplet microfluidics bears significant value in an extremely wide range of area. In this review, we provide… read more here.
Keywords: droplet; emerging droplet; chemistry; droplet microfluidics ... See more keywords
Programmable Droplet Microfluidics Based on Machine Learning and Acoustic Manipulation
Sign Up to like & getrecommendations! Published in 2022 at "Langmuir"
DOI: 10.1021/acs.langmuir.2c01061
Abstract: Typical microfluidic devices are application-specific and have to be carefully designed to implement the necessary functionalities for the targeted application. Programmable microfluidic chips try to overcome this by offering reconfigurable functionalities, allowing the same chip… read more here.
Keywords: programmable droplet; manipulation; droplet microfluidics; machine learning ... See more keywords
Composite Multifunctional Micromotors from Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b11976
Abstract: Inspired by natural biological machines, lots of effort has been invested in developing artificially functional micromotors which can convert energy into movement for carrying out tasks in diverse areas. Here, we present a capillary microfluidic… read more here.
Keywords: micromotors droplet; composite multifunctional; multifunctional micromotors; droplet microfluidics ... See more keywords
Engineering Micromotors with Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.9b00731
Abstract: Micromotors have promising potential in applications ranging from environmental remediation to targeted drug delivery and noninvasive microsurgery. However, there are inadequacies in the fabrication of artificial micromotors to improve the design of structure and composition… read more here.
Keywords: micromotors droplet; engineering micromotors; droplet microfluidics;
Screening Clones for Monoclonal Antibody Production Using Droplet Microfluidics Interfaced to Electrospray Ionization Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.3c00055
Abstract: As one of the most critical steps in process development for protein therapeutics, clone selection and cell culture optimization require a large number of samples to be screened for high titer and desirable molecular profiles.… read more here.
Keywords: mass spectrometry; droplet; droplet microfluidics; spectrometry screening ... See more keywords
Drug screening of cancer cell lines and human primary tumors using droplet microfluidics
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08831-z
Abstract: Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage cancer patients whose tumors are… read more here.
Keywords: drug; drug screening; cancer cell; cancer ... See more keywords
Click Chemistry Approaches to Expand the Repertoire of PEG-based Fluorinated Surfactants for Droplet Microfluidics.
Sign Up to like & getrecommendations! Published in 2018 at "RSC advances"
DOI: 10.1039/c8ra01254g
Abstract: We report the novel and simplified synthesis of fluorinated surfactants for droplet microfluidics. The range of applications of droplet microfluidics has greatly expanded during the last decade thanks to its ability to manipulate and process… read more here.
Keywords: fluorinated surfactants; peg; chemistry; droplet microfluidics ... See more keywords