Identification of lipid droplet targeting motifs and mechanisms for lipolytic inhibitors G0S2 and HIG2.
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DOI: 10.1242/jcs.260236
Abstract: G0S2 and HIG2 are two selective inhibitors of ATGL, the key enzyme for intracellular lipolysis. While G0S2 regulates triglyceride (TG) mobilization in adipocytes and hepatocytes, HIG2 functions to enhance intracellular TG accumulation under hypoxic conditions.… read more here.
Keywords: g0s2 hig2; identification lipid; hig2; lipid droplet ... See more keywords