Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner
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DOI: 10.1126/sciadv.abo2510
Abstract: Hepatic steatosis is a major etiological factor in hepatocellular carcinoma (HCC), but factors causing lipid accumulation leading to HCC are not understood. We identify BNIP3 (a mitochondrial cargo receptor) as an HCC suppressor that mitigates… read more here.
Keywords: droplet turnover; hepatocellular carcinoma; bnip3; growth ... See more keywords