Selective Accumulation to Tumor Cells with Coacervate Droplets Formed from a Water-Insoluble Acrylate Polymer.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01343
Abstract: Selective targeting of specific cells without the use of biological ligands has not been achieved. In the present study, we revealed that the coacervate droplets formed from poly(2-methoxyethyl acrylate) (PMEA) and its derivatives selectively accumulated… read more here.
Keywords: pmea derivatives; water; tumor cells; droplets formed ... See more keywords
Dynamic metastable long-living droplets formed by sticker-spacer proteins
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.56159
Abstract: Multivalent biopolymers phase separate into membrane-less organelles (MLOs) which exhibit liquid-like behavior. Here, we explore formation of prototypical MOs from multivalent proteins on various time and length scales and show that the kinetically arrested metastable… read more here.
Keywords: long living; living droplets; sticker spacer; formed sticker ... See more keywords