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Published in 2022 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2022.01.023
Abstract: Bioconjugation with polyethylene glycol (PEG) is important for protein drug development as it has improved biological stability. In contrast, proteins including PEGylated ones are susceptible to physicochemical stresses. Particularly, protein drugs in solution may form…
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Keywords:
peg ova;
dropping stress;
subvisible particles;
antibody production ... See more keywords