An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2069325
Abstract: ABSTRACT We exploited bacterial infection assays using the fruit fly Drosophila melanogaster to identify anti-infective compounds that abrogate the pathological consequences in the infected hosts. Here, we demonstrated that a pyridine-3-N-sulfonylpiperidine derivative (4a) protects Drosophila… read more here.
Keywords: chelating sulfonamide; drosophila based; iron; iron chelating ... See more keywords