γ-Oryzanol mitigates oxidative stress and prevents mutant SOD1-Related neurotoxicity in Drosophila and cell models of amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.107777
Abstract: Oxidative stress plays a critical role in mutant copper/zinc superoxide dismutase 1 (SOD1)-linked amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease characterized by selective loss of motor neurons. Thus, an anti-oxidative stress remedy might be… read more here.
Keywords: cell models; amyotrophic lateral; stress; drosophila cell ... See more keywords
Generation of genome-modified Drosophila cell lines using SwAP
Sign Up to like & getrecommendations! Published in 2017 at "Fly"
DOI: 10.1080/19336934.2017.1372068
Abstract: ABSTRACT The ease of generating genetically modified animals and cell lines has been markedly increased by the recent development of the versatile CRISPR/Cas9 tool. However, while the isolation of isogenic cell populations is usually straightforward… read more here.
Keywords: lines using; cell lines; generation; drosophila cell ... See more keywords