Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants
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DOI: 10.1242/bio.059376
Abstract: ABSTRACT Filamins are large proteins with actin-binding properties. Mutations in FLNC, one of the three filamin genes in humans, have recently been implicated in dominant cardiomyopathies, but the underlying mechanisms are not well understood. Here,… read more here.
Keywords: crispr cas9; drosophila crispr; function; filamin ... See more keywords