Articles with "drosophila gck" as a keyword



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Functional Inactivation of Drosophila GCK Orthologs Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22020918

Abstract: Maturity-onset diabetes of the young (MODY) type 2 is caused by heterozygous inactivating mutations in the gene encoding glucokinase (GCK), a pivotal enzyme for glucose homeostasis. In the pancreas GCK regulates insulin secretion, while in… read more here.

Keywords: drosophila gck; genomic instability; mody; gck ... See more keywords