Beta-guanidinopropionic acid does not extend Drosophila lifespan
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.101040
Abstract: Activation of AMP activated protein kinase (AMPK) signaling has been demonstrated to extend lifespan and improve healthspan across multiple species. This suggests pharmaceutical approaches to increase AMPK hold the potential to modify the aging process… read more here.
Keywords: drosophila; drosophila lifespan; beta guanidinopropionic; lifespan ... See more keywords
Metabolome analysis of effect of aspirin on Drosophila lifespan extension
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.04.010
Abstract: Abstract Effective approaches for drug development involve the repurposing of existing drugs which are already approved by the FDA. Aspirin has been shown to have many health benefits since its discovery as a nonsteroidal anti‐inflammatory… read more here.
Keywords: aspirin treated; metabolism; drosophila lifespan; analysis ... See more keywords
Regulation of Drosophila Lifespan by bellwether Promoter Alleles
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04530-x
Abstract: Longevity varies among individuals, but how natural genetic variation contributes to variation in lifespan is poorly understood. Drosophila melanogaster presents an advantageous model system to explore the genetic underpinnings of longevity, since its generation time… read more here.
Keywords: drosophila lifespan; haplotype; bellwether promoter; promoter ... See more keywords