Drotaverine hydrochloride gastroretentive floating mini-tablets: Formulation, in-vitro and in-vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101733
Abstract: Abstract Drotaverine hydrochloride (DRH) is an antispasmodic drug which has a short residence in the intestine during diarrhea that prompts poor bioavailability and frequent dosing. The aim of the present study was to increase the… read more here.
Keywords: sodium; drotaverine hydrochloride; mini tablets; floating mini ... See more keywords
Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome
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DOI: 10.1097/md.0000000000011478
Abstract: Abstract This retrospective study investigated the effectiveness and safety of neuromuscular electrical stimulation (NMES) as an adjunctive therapy to drotaverine hydrochloride (DHC) in patients with diarrhea-predominant irritable bowel syndrome (BP-IBS). A total of 108 patient… read more here.
Keywords: adjunctive therapy; electrical stimulation; therapy drotaverine; drotaverine hydrochloride ... See more keywords
Drotaverine Hydrochloride Superporous Hydrogel Hybrid System: a Gastroretentive Approach for Sustained Drug Delivery and Enhanced Viscoelasticity.
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02280-2
Abstract: This study aims to prepare drotaverine hydrochloride superporous hydrogel hybrid systems (DSHH systems) to prolong its residence time in the stomach, provide extended release and reduce its frequency of administration. Drotaverine hydrochloride (DRH) is a… read more here.
Keywords: hydrogel hybrid; superporous hydrogel; approach sustained; drotaverine hydrochloride ... See more keywords
Compatibility of Drotaverine Hydrochloride with Ibuprofen and Ketoprofen Nonsteroidal Anti-Inflammatory Drugs Mixtures
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DOI: 10.3390/ma15031244
Abstract: Formulations with two or more active pharmaceutical ingredients (APIs) are a researched trend due to their convenient use compared with multiple medications. Moreover, drug-drug combinations may have a synergistic effect. Drotaverine hydrochloride (D-HCl) is commonly… read more here.
Keywords: drotaverine hydrochloride; drug; hcl; ibuprofen ketoprofen ... See more keywords
UV Spectrophotometric estimation of Drotaverine hydrochloride by zero order and area under curve methods in bulk and Pharmaceutical Dosage Form
Sign Up to like & getrecommendations! Published in 2018 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2018.01014.4
Abstract: Simple and precise UV spectrophotometric methods by UV spectroscopy and area under curve [AUC] – in zero order derivative spectrum have been developed and validated for the estimation of drotaverine hydrochloride in pharmaceutical formulation. The… read more here.
Keywords: area curve; drotaverine hydrochloride; zero order;