Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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DOI: 10.1016/j.celrep.2019.07.031
Abstract: SUMMARY Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRasG12V promotes mitochondrial fragmentation and tumor growth through Erk phosphorylation of the mitochondrial… read more here.
Keywords: drp1 promotes; kras driven; growth; tumor growth ... See more keywords