Analysis of drug adverse events in elderly patients based on the Japanese Adverse Drug Event Report Database
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13670
Abstract: Compared with the general adult population, pharmacokinetics and changes in drug responsiveness occur to a greater extent in the elderly. Interactions may occur between drugs used in combination to treat various diseases and may cause… read more here.
Keywords: drug adverse; analysis drug; elderly patients; patients based ... See more keywords
Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220959598
Abstract: Hepatic and cardiac drug adverse effects are among the leading causes of attrition in drug development programs, in part due to predictive failures of current animal or in vitro models. Hepatocytes and cardiomyocytes differentiated from… read more here.
Keywords: drug adverse; cellular microsystems; drug; differentiation ... See more keywords