Characterization, epidemiology and risk factors of multiple drug allergy syndrome and multiple drug intolerance syndrome: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12190
Abstract: Abstract Background Multiple drug allergy and multiple drug intolerance syndrome (MDAS/MDIS) labels are an impediment to clinical care and knowledge regarding these conditions is limited. This systematic review investigated the characterization, epidemiology, risk factors, clinical… read more here.
Keywords: methodology; multiple drug; risk; drug allergy ... See more keywords
Synthesis of skeletally diverse β-lactam haptens for the in vitro diagnosis of IgE-mediated drug allergy.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01677j
Abstract: We present the first synthesis of β-lactam-derived haptens, leveraging the principles of diversity-oriented synthesis to discover compounds for drug allergy in vitro testing. We designed, synthesised, and performed in vitro immunological evaluation on 18 structurally… read more here.
Keywords: synthesis skeletally; lactam; drug allergy; synthesis ... See more keywords
506 Allergy Related Clinical Prescribing Alerts in an Electronic Health Record (EHR) System: a descriptive study
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Pharmacy Practice"
DOI: 10.1093/ijpp/riad021.048
Abstract: Globally, allergic responses to medications is a growing concern (1), can result in adverse outcomes of differing levels of severity for patients and if undetected at point of prescription, increase patient risk and potentially increase… read more here.
Keywords: analysis; drug allergy; drug; study ... See more keywords
Global patterns of drug allergy-induced fatalities: a wake-up call to prevent avoidable deaths
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000835
Abstract: Purpose of review To identify patterns and key issues though a systematic review in order to support prevention strategies and reduce avoidable deaths related to drug-induced anaphylaxis (DAF). Recent findings DAF rate has been estimated… read more here.
Keywords: call prevent; drug allergy; avoidable deaths; wake call ... See more keywords
Pearls for practice from the 2022 joint task force drug allergy practice parameter
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001240
Abstract: Purpose of review To review updated recommendations in the 2022 Drug Allergy Practice Parameters for the evaluation and management of drug hypersensitivity reactions. Recent findings Adverse drug reactions have become increasingly prominent with the advent… read more here.
Keywords: practice; allergy practice; drug allergy; drug ... See more keywords
Maternal known drug allergy and long‐term dermatological morbidity of the offspring
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13356
Abstract: Drug allergy is associated with adverse short‐term perinatal outcomes such as caesarian delivery and preterm delivery. The aim of the present study was to determine whether being born to a mother with known drug allergy… read more here.
Keywords: drug allergy; term; dermatological morbidity;
Immunomodulatory and/or immunosuppressive drugs should not be stopped prior to skin tests for the assessment of drug allergy
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20901
Abstract: The use of immunomodulatory and/or immunosuppressive therapy (IT) is increasingly common in the management of chronic inflammatory disease. Skin reactions to any drug (IT or not) are not rare in these patients, justifying allergological investigations.… read more here.
Keywords: immunosuppressive drugs; drug allergy; drug; immunomodulatory immunosuppressive ... See more keywords
In vitro diagnostic testing for drug allergy in children
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13955
Abstract: Diagnosing Drug Hypersensitivity Reactions (DHRs) could be a complicated process especially in children, since allergic‐like manifestation at this age is more often the expression of concomitant infections rather than a actual DHRs. In vivo tests… read more here.
Keywords: diagnostic testing; allergy; vitro diagnostic; drug allergy ... See more keywords
New perspectives on drug allergy in children
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13957
Abstract: One of the first questions that medical doctors and likewise nurses ask patients when performing a medical history is: Do you have any drug allergies? It is interesting that even at Medical School, students learn… read more here.
Keywords: allergy children; drug allergy; dhrs; drug ... See more keywords
Analysis of the Safety of Drug Allergy Workups in a Spanish University Hospital: Drug Characteristics, Type of Reaction, and Patients’ Age at the Initial Assessment
Sign Up to like & getrecommendations! Published in 2023 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000528197
Abstract: Introduction: The drug provocation test (DPT) is the gold standard for the drug allergy workup; however, it is not free from severe adverse reactions. Our aim was to obtain robust data that predict a reaction… read more here.
Keywords: university hospital; reaction; allergy workups; allergy ... See more keywords
Dietary parameters in patients with drug allergy: Assessing dietary inflammatory index
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277046
Abstract: Background Research on the increasing incidence of allergic diseases evidenced the role of diet as a potential key factor. Diet can modulate the low-grade systemic inflammation related to obesity and several diseases. There are no… read more here.
Keywords: inflammatory; parameters patients; drug allergy; drug ... See more keywords