The use of molecular descriptors in the development of co‐amorphous formulations
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DOI: 10.1016/j.ejps.2018.04.014
Abstract: ABSTRACT Co‐amorphous systems consisting of a drug and an amino acid have been investigated extensively for the enhancement of drug solubility and amorphous stability. The purpose of this study is to investigate which molecular descriptors… read more here.
Keywords: amino; amino acid; acid combinations; molecular descriptors ... See more keywords
The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations.
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DOI: 10.1021/acs.molpharmaceut.8b00650
Abstract: The improved physical stability associated with coamorphous drug-amino acid (AA) formulations may indicate a decrease in mobility of the amorphous drug molecules, compared to the neat amorphous form of the drug. Since the characteristic glass… read more here.
Keywords: amino acid; acid formulations; coamorphous systems; drug ... See more keywords