Automated spheroid generation, drug application and efficacy screening using a deep learning classification: a feasibility study
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67960-0
Abstract: The last two decades saw the establishment of three-dimensional (3D) cell cultures as an acknowledged tool to investigate cell behaviour in a tissue-like environment. Cells growing in spheroids differentiate and develop different characteristics in comparison… read more here.
Keywords: automated spheroid; deep learning; drug; spheroid generation ... See more keywords
The continuous morbidostat: A chemostat with controlled drug application to select for drug resistance mutants
Sign Up to like & getrecommendations! Published in 2020 at "Communications on Pure and Applied Analysis"
DOI: 10.3934/cpaa.2020011
Abstract: The morbidostat is a bacteria culture device that progressively increases antibiotic drug concentration and maintains a constant challenge for study of evolutionary pathway. The operation of a morbidostat under serial transfer has been analyzed previously.… read more here.
Keywords: morbidostat chemostat; drug; drug application; continuous morbidostat ... See more keywords