Anticholinergic/sedative drug burden predicts worse memory acquisition in older racially/ethnically diverse patients with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5173
Abstract: Anticholinergic/sedative drug use, measured by the Drug Burden Index (DBI), is linked to cognitive impairment in older adults. Yet, studies on the DBI's association with neuropsychological functioning are lacking, especially in underserved groups at increased… read more here.
Keywords: anticholinergic sedative; drug; type diabetes; drug burden ... See more keywords
Is anticholinergic and sedative drug burden associated with postdischarge institutionalization in community‐dwelling older patients acutely admitted to hospital? A Norwegian registry‐based study
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5590
Abstract: Investigate the association between anticholinergic (AC) and sedative (SED) drug burden before hospitalization and postdischarge institutionalization (PDI) in community‐dwelling older patients acutely admitted to hospital. read more here.
Keywords: anticholinergic sedative; dwelling older; community dwelling; postdischarge institutionalization ... See more keywords
Drug Burden Index and change in cognition over time in community-dwelling older men: the CHAMP study
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DOI: 10.1080/07853890.2016.1252053
Abstract: Abstract Objective: Anticholinergic and sedative medications are associated with acute cognitive impairment, but the long-term impact on change in cognition is unclear. This study investigated the effect of anticholinergic and sedative medications, quantified using the… read more here.
Keywords: anticholinergic sedative; time; sedative medications; drug burden ... See more keywords
Drug burden index to define the burden of medicines in older adults with intellectual disabilities: An observational cross‐sectional study
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13479
Abstract: The drug burden index (DBI) is a dose‐related measure of anticholinergic and sedative drug exposure. This cross‐sectional study described DBI in older adults with intellectual disabilities (ID) and the most frequently reported therapeutic classes contributing… read more here.
Keywords: cross sectional; burden index; sectional study; drug ... See more keywords
Using the Drug Burden Index to identify older adults at highest risk for medication-related falls
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DOI: 10.1186/s12877-020-01598-5
Abstract: Background The Drug Burden Index (DBI) was developed to assess patient exposure to medications associated with an increased risk of falling. The objective of this study was to examine the association between the DBI and… read more here.
Keywords: risk; burden index; dbi scores; drug burden ... See more keywords
Anti-Cholinergic Drug Burden Among Ambulatory Elderly Patients in a Nigerian Tertiary Healthcare Facility
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.580152
Abstract: Background: The use of drugs with anticholinergic effects among elderly patients is associated with adverse clinical outcomes. There is paucity of information about anticholinergic drug burden among Nigerian elderly population. Objectives: To determine the anticholinergic… read more here.
Keywords: anticholinergic effects; burden among; anticholinergic burden; drug burden ... See more keywords