Stressing the Role of DNA as a Drug Carrier: Synthesis of DNA-Drug Conjugates through Grafting Chemotherapeutics onto Phosphorothioate Oligonucleotides.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201807533
Abstract: To stress the role of deoxyribonucleic acid (DNA) as a drug carrier, an efficient conjugation strategy in which chemotherapeutics can be grafted onto a phosphorothiolated DNA backbone through the reaction between the phosphorothioate group (PS)… read more here.
Keywords: drug carrier; dna; ptx; drug ... See more keywords
“Drug‐Carrier” Synergy Therapy for Amyloid‐β Clearance and Inhibition of Tau Phosphorylation via Biomimetic Lipid Nanocomposite Assembly
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202106072
Abstract: Amyloid‐β (Aβ) toxicity is considered to be companioned by Tau phosphorylation in Alzheimer's disease (AD). The clinical AD therapy is usually subjected to low blood‐brain barrier (BBB) penetration and complex interaction mechanisms between Aβ and… read more here.
Keywords: tau; synergy therapy; therapy; synergy ... See more keywords
Magnetic Biohybrid Robots as Efficient Drug Carrier to Generate Plant Cell Clones.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200208
Abstract: Micro/nanorobots represent a new generation of micromachines that can accomplish various tasks, such as loading and transporting specific targets or pharmaceuticals for a given application. Biohybrid robots consisting of biological cells (bacteria, sperm, and microalgae)… read more here.
Keywords: magnetic biohybrid; biohybrid robots; generate; robots efficient ... See more keywords
Fluorescent quantum dots: An insight on synthesis and potential biological application as drug carrier in cancer
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.100962
Abstract: Quantum dots (QDs) are nanocrystals of semiconducting material possessing quantum mechanical characteristics with capability to get conjugated with drug moieties. The particle size of QDs varies from 2 to 10 nm and can radiate a… read more here.
Keywords: drug carrier; drug; qds; quantum dots ... See more keywords
Synthesis of β-cyclodextrin-PEG-G molecules to delay tumor growth and application of β-cyclodextrin-PEG-G aggregates as drug carrier.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115478
Abstract: The clinical use of many chemotherapeutic drugs is considerably greatly limited due to their serious side effects. This problem can be solved by using a low-toxic or nontoxic drug carrier that exhibits excellent performance in… read more here.
Keywords: peg aggregates; drug carrier; peg; cyclodextrin peg ... See more keywords
Folic acid-grafted bovine serum albumin decorated graphene oxide: An efficient drug carrier for targeted cancer therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2016.11.097
Abstract: Targeting drug carrier systems based on graphene oxide (GO) are of great interest, since it can selectively deliver anticancer drugs to tumor cells, and enhance therapeutic activities with minimized side effects. However, direct grafting target… read more here.
Keywords: graphene oxide; folic acid; drug carrier; bsa ... See more keywords
Exfoliated graphene nanosheets: pH-sensitive drug carrier and anti-cancer activity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.03.057
Abstract: A straightforward and facile method for the exfoliation of graphene sheets using poly(vinylpyrrolidone) nanoparticles of an average size of 42nm was developed and their dual role as pH-sensitive drug carrier and anti-cancer agent was evaluated.… read more here.
Keywords: drug carrier; sensitive drug; drug; cancer ... See more keywords
Adaptive Chitosan Hollow Microspheres as Efficient Drug Carrier.
Sign Up to like & getrecommendations! Published in 2017 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b00592
Abstract: Smart drug carrier with function-oriented adaptations is highly desired due to its unique properties in medical applications. Herein, adaptive chitosan hollow microspheres (CHM) are fabricated by employing interfacial Schiff-base bonding reaction. Hydrophilic macromolecules of glycol… read more here.
Keywords: adaptive chitosan; hollow microspheres; drug carrier; drug ... See more keywords
Biodegradable Magnetic Molecularly Imprinted Anticancer Drug Carrier for the Targeted Delivery of Docetaxel
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03299
Abstract: Molecularly imprinted biodegradable polymers are receiving considerable attention in drug delivery due to their ability of targeted recognition and biocompatibility. This study reports the synthesis of a novel fluorescence-active magnetic molecularly imprinted drug carrier (MIDC)… read more here.
Keywords: molecularly imprinted; magnetic molecularly; drug carrier; drug ... See more keywords
Microfluidics for core–shell drug carrier particles – a review
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d0ra08607j
Abstract: Core–shell drug-carrier particles are known for their unique features. Due to the combination of superior properties not exhibited by the individual components, core–shell particles have gained a lot of interest. The structures could integrate core… read more here.
Keywords: drug; shell drug; drug carrier; core shell ... See more keywords
Multi-functional magnetic nanoparticles as an effective drug carrier for the controlled anti-tumor treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomaterials Applications"
DOI: 10.1177/0885328217748023
Abstract: Because of the complications and mutability of cancers, combination of chemotherapy and other therapy with multi-mechanisms would be a bright future for the treatment of cancer. Thus, development of multi-functional tumor-targeted drug delivery systems with… read more here.
Keywords: drug carrier; drug; multi functional; anti tumor ... See more keywords