Summary statistics for drug concentrations in post-mortem femoral blood representing all causes of death.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2655
Abstract: Concentration distributions for 183 drugs and metabolites frequently found in post-mortem (PM) femoral venous blood were statistically characterized based on an extensive database of 122 234 autopsy cases investigated during an 18-year period in a… read more here.
Keywords: mortem femoral; drug; post mortem; causes death ... See more keywords
Local vasoregulative interventions impact drug concentrations in the skin after topical laser‐assisted delivery
Sign Up to like & getrecommendations! Published in 2022 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23558
Abstract: The ability of ablative fractional lasers (AFL) to enhance topical drug uptake is well established. After AFL delivery, however, drug clearance by local vasculature is poorly understood. Modifications in vascular clearance may enhance AFL‐assisted drug… read more here.
Keywords: assisted delivery; drug concentrations; afl assisted; vasoregulative interventions ... See more keywords
Antidepressants in breast milk; comparative analysis of excretion ratios
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Women's Mental Health"
DOI: 10.1007/s00737-018-0905-3
Abstract: Despite increasing prescription rates of antidepressants in pregnant and breastfeeding women over the past decades, evidence of drug exposure for neonates through lactation is very sparse. Concentrations of three antidepressants citalopram, sertraline, and venlafaxine were… read more here.
Keywords: milk; drug; daily dosage; drug concentrations ... See more keywords
Indexed plasma drug concentrations for drug adherence screening in hypertensive patients.
Sign Up to like & getrecommendations! Published in 2018 at "Annales de cardiologie et d'angeiologie"
DOI: 10.1016/j.ancard.2018.04.020
Abstract: AIM Due to its high sensitivity, qualitative plasma drug screening by liquid chromatography/tandem mass spectrometry may not be able to distinguish same-day drug intake from drug use on preceding days and cause misclassifications of drug… read more here.
Keywords: drug adherence; drug; drug concentrations; hypertensive patients ... See more keywords
Postmortem blood sampling-Comparison of drug concentrations at different sample sites.
Sign Up to like & getrecommendations! Published in 2017 at "Forensic science international"
DOI: 10.1016/j.forsciint.2017.07.006
Abstract: Drug concentrations in postmortem blood samples can differ considerably, depending on the sample site - a phenomenon named postmortem redistribution. In this study, blood samples from 48 cases of suspected intoxications were collected during autopsy… read more here.
Keywords: postmortem blood; ratio; blood; drug concentrations ... See more keywords
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw534
Abstract: Background Toxicities due to anti-TB treatment frequently occur among TB/HIV-coinfected patients. Objectives To determine the association between anti-TB drug concentrations and the occurrence of hepatotoxicity and peripheral neuropathy among TB/HIV-coinfected patients. Methods TB/HIV-coinfected patients were… read more here.
Keywords: among hiv; drug; hiv coinfected; hepatotoxicity ... See more keywords
A Comparison of High Drug Concentrations in Impaired Driving and Postmortem Casework in Harris County, Texas.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac032
Abstract: Drug-impaired driving is a growing public safety issue. Addressing impairment due to drugs other than ethanol can be challenging for forensic toxicologists as many factors need to be considered including the type of drug(s), drug-drug… read more here.
Keywords: postmortem; dwi duid; drug concentrations; impaired driving ... See more keywords
Monitoring antihypertensive drug concentrations to determine nonadherence in hypertensive patients with or without a kidney transplant.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of hypertension"
DOI: 10.1097/hjh.0000000000003459
Abstract: BACKGROUND Nonadherence to antihypertensive drugs (AHDs) is a major contributor to pseudo-resistant hypertension. The primary objective of this study was to determine the prevalence of nonadherence to AHDs among patients visiting the nephrology and vascular… read more here.
Keywords: drug concentrations; kidney transplant; adherence;
High-precision monitoring of and feedback control over drug concentrations in the brains of freely moving rats
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adg3254
Abstract: Knowledge of drug concentrations in the brains of behaving subjects remains constrained on a number of dimensions, including poor temporal resolution and lack of real-time data. Here, however, we demonstrate the ability of electrochemical aptamer-based… read more here.
Keywords: concentrations brains; freely moving; brains freely; drug concentrations ... See more keywords
Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes
Sign Up to like & getrecommendations! Published in 2023 at "mBio"
DOI: 10.1128/mbio.00227-23
Abstract: Antifungal drug tolerance differs from drug resistance: tolerant cells grow slowly in drug, while resistant cells usually grow well, due to mutations in a few known genes. More than half of Candida albicans clinical isolates… read more here.
Keywords: drug tolerance; physiology; drug concentrations; resistance ... See more keywords
Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment
Sign Up to like & getrecommendations! Published in 2017 at "Respiration"
DOI: 10.1159/000470916
Abstract: Background: Combination therapy with the phosphodiesterase type 5 inhibitors (PDE-5i) sildenafil or tadalafil and the endothelin receptor antagonists (ERA) bosentan, ambrisentan, or macitentan may cause mutual pharmacokinetic interactions in patients with pulmonary arterial hypertension (PAH).… read more here.
Keywords: combination; mom; drug concentrations; plasma drug ... See more keywords