Generic instruments for drug discontinuation in primary care: A systematic review
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DOI: 10.1111/bcp.14287
Abstract: Aims The aim of this systematic review was to identify generic instruments for drug discontinuation in patients with polypharmacy in the primary care setting. Methods We systematically searched PubMed and EMBASE, 8 guideline databases (AWMF,… read more here.
Keywords: generic instruments; instruments drug; systematic review; drug ... See more keywords
Trials evaluating drug discontinuation: a scoping review sub-analysis focusing on outcomes and research questions
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DOI: 10.1186/s12874-025-02597-z
Abstract: The widespread use of long-term pharmacological treatments for chronic conditions has led to polypharmacy, raising concerns about adverse effects and interactions. Deprescribing, the discontinuation of drugs with unfavorable benefit-risk ratios, is gaining attention. Studies evaluating… read more here.
Keywords: discontinuation; justification; drug; drug discontinuation ... See more keywords
Trajectory of the body weight after drug discontinuation in the treatment of anti-obesity medications
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DOI: 10.1186/s12916-025-04200-0
Abstract: Globally, obesity has emerged as a significant public health concern, imposing detrimental impacts on human health. The purpose of our study was to explore the long-term effects of anti-obesity medications (AOMs) on body weight and… read more here.
Keywords: weight regain; treatment; obesity; discontinuation ... See more keywords
Dosing, drug reduction, drug interruption, and drug discontinuation rates among U.S. FDA approved tyrosine kinase inhibitors.
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DOI: 10.1200/jco.2021.39.15_suppl.3112
Abstract: 3112 Background: The advent of tyrosine kinase inhibitors (TKIs) has altered the therapeutic landscape of multiple hematological and solid malignancies. FDA approved starting doses of TKIs are based on the recommended phase 2 dose (RP2D)… read more here.
Keywords: fda approved; drug; discontinuation rates; drug discontinuation ... See more keywords
Understanding Study Drug Discontinuation Through EUCLID
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.947645
Abstract: Introduction Disparities in the care and outcomes of peripheral artery disease (PAD) have been well-established. In part this is due to disparities in enrollment of PAD trial cohorts. However, less attention has been paid to… read more here.
Keywords: drug; study drug; drug discontinuation; understanding study ... See more keywords