Computational Modeling of Drug Dissolution in the Human Stomach
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DOI: 10.3389/fphys.2021.755997
Abstract: A computational model of drug dissolution in the human stomach is developed to investigate the interaction between gastric flow and orally administrated drug in the form of a solid tablet. The stomach model is derived… read more here.
Keywords: dissolution human; dissolution; human stomach; drug dissolution ... See more keywords
A Critical Overview of FDA and EMA Statistical Methods to Compare In Vitro Drug Dissolution Profiles of Pharmaceutical Products
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DOI: 10.3390/pharmaceutics13101703
Abstract: A drug dissolution profile is one of the most critical dosage form characteristics with immediate and controlled drug release. Comparing the dissolution profiles of different pharmaceutical products plays a key role before starting the bioequivalence… read more here.
Keywords: drug dissolution; dissolution profiles; pharmaceutical products; dissolution ... See more keywords
Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity
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DOI: 10.3390/pharmaceutics14112350
Abstract: Estimating the dissolution behavior of a solid in the nasal mucus is challenging for solid dosage forms designed for the nasal application as the solid dissolves into nasal mucus and permeates through the mucosa. In… read more here.
Keywords: dissolution; vitro evaluation; drug dissolution; evaluation system ... See more keywords