Barriers to Drug Distribution into the Perinatal and Postnatal Brain
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2375-8
Abstract: Drug bioavailability to the developing brain is a major concern in the treatment of neonates and infants as well as pregnant and breast-feeding women. Central adverse drug reactions can have dramatic consequences for brain development,… read more here.
Keywords: blood brain; drug; drug distribution; brain ... See more keywords
Imaging and spatially resolved quantification of drug distribution in tissues by mass spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2018.05.007
Abstract: Mass spectrometry imaging (MSI) is a powerful label-free technique for visualizing drug and metabolite distributions in biological tissues. In this review, we discuss recent developments in MSI and spatial profiling technologies to visualize and quantify… read more here.
Keywords: drug; drug distribution; spatially resolved; mass spectrometry ... See more keywords
Influence of the drug distribution in electrospun gliadin fibers on drug‐release behavior
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.06.017
Abstract: Abstract Drug distribution within its carrier in a solid dosage form often generates a profound influence on its release profile, particularly when the physicochemical properties of the carrier are exploited to manipulate drug release behavior.… read more here.
Keywords: gliadin; drug; drug release; drug distribution ... See more keywords
Quantitative analysis of drug distribution in heterogeneous tissues using dual‐stacking capillary electrophoresis–mass spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15988
Abstract: Intratumour heterogeneity frequently leads to drug resistance, which is a major issue in drug discovery. Drug distribution is one of the key factors for elucidating the resistance mechanism; however, quantitative and regional drug measurement is… read more here.
Keywords: heterogeneous tissues; analysis drug; quantitative analysis; drug distribution ... See more keywords
Hybrid Governance in Online Drug Distribution
Sign Up to like & getrecommendations! Published in 2022 at "Contemporary Drug Problems"
DOI: 10.1177/00914509221101212
Abstract: A growing share of illicit drug dealing occurs on online platforms. Technological innovations, such as encryption and anonymous payments, have enabled new and more complex ways of organizing transactions. This conceptual essay advances the study… read more here.
Keywords: hybrid governance; governance; drug distribution; online drug ... See more keywords
Models and Algorithms for the Refinement of Therapeutic Approaches for Retinal Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13050975
Abstract: We are developing a Virtual Eye for in silico therapies to accelerate research and drug development. In this paper, we present a model for drug distribution in the vitreous body that enables personalized therapy in… read more here.
Keywords: retinal diseases; therapy; drug distribution; model ... See more keywords
Recent Studies of Artificial Intelligence on In Silico Drug Distribution Prediction
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031815
Abstract: Drug distribution is an important process in pharmacokinetics because it has the potential to influence both the amount of medicine reaching the active sites and the effectiveness as well as safety of the drug. The… read more here.
Keywords: drug distribution; artificial intelligence; distribution prediction; distribution ... See more keywords
The Impact of Surface Drug Distribution on the Acoustic Behavior of DOX-Loaded Microbubbles
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13122080
Abstract: Previous studies have reported substantial improvement of microbubble (MB)-mediated drug delivery with ultrasound when drugs are loaded onto the MB shell compared with a physical mixture. However, drug loading may affect shell properties that determine… read more here.
Keywords: drug; drug distribution; shell; impact surface ... See more keywords