Bayesian approach to investigate a two-state mixed model of COPD exacerbations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacokinetics and Pharmacodynamics"
DOI: 10.1007/s10928-019-09643-6
Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic obstructive disease of the airways. An exacerbation of COPD is defined as shortness of breath, cough, and sputum production. New therapies for COPD exacerbations are examined in… read more here.
Keywords: state; copd exacerbations; model; drug effect ... See more keywords
Therapeutic Drug Monitoring of Second-Generation Antipsychotics for the Estimation of Early Drug Effect in First-Episode Psychosis: A Cross-sectional Assessment
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000480
Abstract: Background: Studies on therapeutic drug monitoring (TDM) of second-generation antipsychotics (SGAs) have provided conflicting results regarding the association between dose, plasma concentrations, and drug effect and have focused rather on analyzing how individual drugs work.… read more here.
Keywords: plasma concentrations; drug; therapeutic drug; drug effect ... See more keywords
Drug Treatment Effect Model Based on MODWT and Hawkes Self-Exciting Point Process
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/4038290
Abstract: In precision medicine, especially in the pharmacodynamic area, the lack of an adequate long-term drug effect monitoring model leads to a quite low robustness to the instant drug treatment. Modelling the effect of drug based… read more here.
Keywords: time; effect; drug effect; model ... See more keywords