Articles with "drug encapsulation" as a keyword



Molecular understanding of interactions, structure, and drug encapsulation efficiency of Pluronic micelles from dissipative particle dynamics simulations

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Published in 2019 at "Colloid and Polymer Science"

DOI: 10.1007/s00396-019-04535-0

Abstract: AbstractIn this work, we employ coarse-grained dissipative particle dynamics simulations with the hydrogen bonds added explicitly to study the drug encapsulation property, structure, and interactions of Pluronic L64/ibuprofen combinations. The coarse-grained simulations reveal that the… read more here.

Keywords: particle dynamics; drug; coarse grained; dissipative particle ... See more keywords

Controlled dual drug release by coaxial electrospun fibers - Impact of the core fluid on drug encapsulation and release.

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Published in 2019 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.12.026

Abstract: Controlled release of hydrophilic drugs from carriers is still faced with problems due to the poor compatibility of such substances with slowly degradable polymers leading to challenges regarding fabrication as well as undesired burst release… read more here.

Keywords: core fluid; drug; drug release; encapsulation release ... See more keywords

Polymerization-Induced Self-Assembly (PISA) for in situ drug encapsulation or drug conjugation in cancer application.

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Published in 2022 at "Journal of colloid and interface science"

DOI: 10.1016/j.jcis.2022.03.044

Abstract: HYPOTHESIS We describe the possibility of using the same block copolymer carriers prepared by PISA for in situ drug encapsulation or drug conjugation. EXPERIMENTS Block copolymers containing poly((ethylene glycol) methacrylate)-co-poly(pentafluorophenyl methacrylate)-b-poly(hydroxypropyl methacrylate) (P((PEGMA-co-PFBMA)-b-PHPMA)) were synthesized… read more here.

Keywords: drug; drug encapsulation; encapsulation drug; situ drug ... See more keywords

Maximizing Aqueous Drug Encapsulation: Small Nanoparticles Formation Enabled by Glycopolymers Combining Glucose and Tyrosine.

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Published in 2024 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.3c12502

Abstract: Highly potent heterocyclic drugs are frequently poorly water soluble, leading to limited or abandoned further drug development. Nanoparticle technology offers a powerful delivery approach by enhancing the solubility and bioavailability of hydrophobic therapeutics. However, the… read more here.

Keywords: drug encapsulation; drug; small nanoparticles; glucose tyrosine ... See more keywords

Silk Fibroin Nanoparticles for Drug Delivery: Effect of Bovine Serum Albumin and Magnetic Nanoparticles Addition on Drug Encapsulation and Release

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Published in 2018 at "Separations"

DOI: 10.3390/separations5020025

Abstract: Silk fibroin nanoparticles were prepared in the present study based on phase separation between silk fibroin and polyvinyl alcohol. The drug encapsulation efficiency of the prepared nanoparticles was examined at a range of concentrations from… read more here.

Keywords: drug; drug encapsulation; silk fibroin; fibroin nanoparticles ... See more keywords