Primary Human Pancreatic Cancer Cells Cultivation in Microfluidic Hydrogel Microcapsules for Drug Evaluation
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206004
Abstract: Chemotherapy is an essential postoperative treatment for pancreatic cancer, while due to the lack of effective drug evaluation platforms, the therapeutic outcomes are hampered by tumor heterogeneity among individuals. Here, a novel microfluidic encapsulated and… read more here.
Keywords: drug evaluation; drug; pancreatic cancer; tumor ... See more keywords
Drug evaluation: mepolizumab in chronic obstructive pulmonary disease.
Sign Up to like & getrecommendations! Published in 2025 at "Immunotherapy"
DOI: 10.1080/1750743x.2025.2504326
Abstract: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality globally, marked by persistent respiratory symptoms and exacerbations. It is now acknowledged to be a heterogeneous disease with respect to clinical expression and key… read more here.
Keywords: disease; drug evaluation; chronic obstructive; mepolizumab ... See more keywords
Recombinant GM-CSF drug evaluation review.
Sign Up to like & getrecommendations! Published in 2025 at "Immunotherapy"
DOI: 10.1080/1750743x.2025.2571020
Abstract: Autoimmune Pulmonary Alveolar Proteinosis (aPAP) is a rare disease characterized by myeloid cell dysfunction, abnormal pulmonary surfactant accumulation, and innate immune deficiency. Pathogenesis is driven by GM-CSF neutralizing autoantibodies (GMAbs) present in high titer in… read more here.
Keywords: drug evaluation; rgm csf; csf; csf drug ... See more keywords
Drug evaluation studies in neonates: how to overcome the current limitations
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DOI: 10.1080/17512433.2018.1439378
Abstract: ABSTRACT Introduction: Regulatory initiatives have stimulated drug research in infants, but the potential impact of drugs to improve health outcome in neonates remains underexplored. Areas covered: In this review, we focus on current limitations in… read more here.
Keywords: current limitations; evaluation studies; drug evaluation; drug ... See more keywords
Therapeutic innovation in oncology: What do you mean? Whereof one cannot speak, thereof one must be silent, L. Wittgenstein
Sign Up to like & getrecommendations! Published in 2025 at "BMC Cancer"
DOI: 10.1186/s12885-025-14922-2
Abstract: The word “innovation” is widely used in healthcare, especially in oncology. Innovation has been reported to impact the drug evaluation process, but there is no consensus regarding the evaluation of innovation. This study aimed to… read more here.
Keywords: oncology; drug evaluation; innovation; cluster ... See more keywords